What are some of the indications of an immune response?

The immune system consists of an integrated constellation of various cell types, each with a specifically designated functional role. In addition, secreted molecules (cytokines) are responsible for interactions, modulations, and regulation of the system. The proper functioning of the immune system depends on its ability to distinguish "self" from "non-self" and "normal" from "abnormal". A healthy immune system, therefore, involves accurate recognition of foreign, harmful invaders and abnormally altered cells within the body followed by a natural, healthy reaction to eliminate them.

The healthy immune system uses powerful weapons designed to kill pathogens (viruses, bacteria and other organisms), destroy abnormal tissue and rid the body of foreign toxic compounds. These weapons of a strong immune system include inflammation, fever, swelling, sweating, etc. This can be temporarily uncomfortable, causing fatigue, altered appetite, aches, pains, nausea, skin rash, etc. These responses are, however, extremely important evidence of an active immune system. For example, failure to develop a fever in the course of a severe infection foretells a poor outcome. Thus, what are sometimes perceived as negative effects of a virus or other pathogen are actually positive manifestations of a strong immune system as it responds appropriately to the challenge.

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